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UID:235@researchweek.unc.edu
DTSTART;TZID=America/New_York:20241021T153000
DTEND;TZID=America/New_York:20241021T170000
DTSTAMP:20240903T151933Z
URL:https://researchweek.unc.edu/events/het-talks/
SUMMARY:Het Talks
DESCRIPTION:Enjoy presentations by this year’s recipients of the Phillip 
 and Ruth Hettleman Prizes for Scholarly Achievement. The talks will provid
 e an engaging look into these distinguished early career scholars’ work.
 \n\nThe late Phillip Hettleman\, a member of the Carolina class of 1921\, 
 and his wife Ruth established their prestigious named award in 1986 to rec
 ognize the achievements of outstanding junior faculty. The recipients of t
 he $8\,000 prize will be recognized at an upcoming Faculty Council Meeting
 .\n\nThis is an in-person event.\n\n2024 Hettleman Winners\nWubin Bai\, Ap
 plied Physical Sciences\, College of Arts and Sciences \n\nResearch: Bai i
 s a rising scholar pioneering in bioelectronic technology\, especially in 
 the realm of implantable and wearable devices and drug delivery. His broad
  background in materials science and biomedical engineering is backing his
  work on next-generation medical devices for improving health and increasi
 ng our understanding of living systems. He has over 65 publications to dat
 e — 17 of those as first author — including many high-impact works. \n
 \nBai combines the materials science of soft responsive materials\, biosen
 sing\, and autonomous dosing with advanced manufacturing\, all within a sy
 stem engineering perspective to make complete solutions. His lab invented 
 a multi-modal patch for deep tissue monitoring and digitally automated dru
 g delivery\, developed 3D multiscale electronic scaffolds for studying org
 anoids\, and designed small soft robots to address challenges of medical i
 mplants\, all of which yielded patents to pursue translation. \n\nImpact: 
 Bai’s goal is to create new technologies for wearable or implantable dev
 ices that can sense physiological quantities to deliver drugs or direct ti
 ssue growth and disappear when no longer needed. His developments enable d
 ozens of microgram-dose drugs to be actively delivered with high precision
 \, serving as a promising solution to improve patient compliance and adher
 ence to a pharmaceutical plan\, increase treatment precision\, and realize
  pharmaceutical intelligence. \n\n\n\nStephanie DeGooyer\, English and Com
 parative Literature\, College of Arts and Sciences \n\nResearch: DeGooyer
 ’s research examines intersections between law and literature from both 
 historical and contemporary perspectives. By looking at eighteenth-century
  literature through the lens of legal and political texts\, and vice versa
 \, she reveals new relationships between the development of the novel and 
 emerging concepts of nationality.  \n\nDeGooyer has two monograph projects
  currently underway and has explored these important issues in two acclaim
 ed books. She has also written three book chapters\, three peer-reviewed a
 rticles in journals\, 14 op-eds and articles of engaged scholarship\, and 
 appeared in 13 interviews and podcasts. She performs both academic and pub
 lic-engaged scholarship with an equally impressive degree of success. \n\n
 Impact: By exploring major issues in their sociohistorical context\, DeGoo
 yer brings to light unexpected continuities\, discrepancies\, and parallel
 s between concepts and policies of immigration\, notions of citizenship\, 
 nationality\, refugees\, asylum in the 18th and 21st centuries. Her resear
 ch is revolutionary in its approach to 18th-century literature and culture
  but is also timely and invaluable to the current understanding of hot-but
 ton topics like immigration policy and law\, political refugees and politi
 cal asylum\, nationality\, nationhood\, and citizenship. \n\nDeGooyer is a
 ctively shaping public discourse on these topics through interviews and po
 dcasts with PBS\, The Nation\, The Guardian\, and Public Books. She also e
 ngages in public humanities activities that elevate the academic profile o
 f both the English and comparative literature department and the Universit
 y and demonstrates the relevance of the humanities in today’s world. \n\
 n\n\nJulia Rager\, Environmental Sciences and Engineering\, Gillings Schoo
 l of Global Public Health \n\nResearch: Rager leads a research team aimed 
 at unraveling relationships between environmental exposures and health out
 comes\, with a focus on complex mixtures — made of many chemicals whose 
 complete composition is unknown — that are becoming more prevalent in th
 e environment. Her laboratory uniquely addresses this goal by coupling adv
 anced computer modeling methods with molecular toxicology approaches. \n\n
 Rager is an expert in public health and human risk assessment\, but also w
 ell-trained and equipped to leverage the latest tools and approaches from 
 the disciplines of genomics\, molecular biology\, and computational scienc
 es. She has produced 90 publications — 22 of which she led as last autho
 r\, and 14 of which included students in her lab as first authors. \n\nImp
 act: The primary mission of Rager’s lab is to integrate data from next-g
 eneration technologies into the regulatory arena to better protect public 
 health. Her findings highlight the importance of regulating human exposure
 s to chemicals based on the best available science enabled through a biolo
 gical analysis method that combines multiple datasets to study complex bio
 logical processes.  \n\nShe has worked on some of the most challenging ong
 oing environmental chemical issues including arsenic\, hexavalent chromium
 \, perfluorinated chemicals\, and wildfire emissions. Her work has been ci
 ted extensively and has been considered in a formal risk assessment proces
 s at the U.S. Environmental Protection Agency. \n\n\n\nCarl Rodriguez\, Ph
 ysics and Astronomy\, College of Arts and Sciences \n\nResearch: Rodriguez
  is an emerging leader in a field that is in its infancy — black holes a
 nd gravitational waves. This year\, he was selected by the American Astron
 omical Society for the Warner Prize\, the highest national award given to 
 early-career astrophysicists. He won for groundbreaking work on the astrop
 hysical origin of the gravitational-wave sources detected by the Laser Int
 erferometer Gravitational-Wave Observatory (LIGO).  \n\nRodriguez’s work
  on the dynamical formation of merging black hole binaries from young star
  clusters\, stellar triples\, and globular clusters — millions of stars 
 tightly bound together — has been key in the community's analysis of the
 se events. His 96 peer-reviewed papers\, 19 of which he led as first autho
 r\, have garnered over 10\,000 citations. \n\nImpact: By carefully studyin
 g the full catalogs of gravitational waves — ripples in spacetime caused
  by large moving objects like black holes — that will be discovered over
  the coming decades\, Rodriguez can learn not only about how black holes f
 orm\, but how stars\, star clusters\, and even galaxies are born and die a
 cross cosmic space and time. \n\n\n\nMark Shen\, Psychiatry\, School of Me
 dicine \n\nResearch: Shen discovered an early biomarker for autism — the
  presence of excessive cerebrospinal fluid (CSF) volume in the brain — t
 hat is detectable by 6 months of age in certain babies\, which is two year
 s before they develop autism. His research since then has focused on how C
 SF cleans the brain of neuroinflammation and how problems with that proces
 s can lead to the development of autism in the first years of life. He has
  led the world’s literature in this field. \n\nShen is now PI of a five-
 year\, NIH-funded study of early CSF pathophysiology\, the brain’s lymph
 atics\, and its downstream effects on brain development\, using neuroimagi
 ng in infants with neurodevelopmental disabilities (NDDs) and mechanistic 
 studies in corresponding mouse models of these NDDs. His NIH grant is the 
 first study of brain lymphatics in children. Shen has published 40 peer-re
 viewed papers\, including eight that were recognized by the NIH as finalis
 ts for “the most significant advances in autism research.” He was also
  named the Early-Career Investigator of the Year by the International Soci
 ety for Autism Research.  \n\nImpact: Behavioral symptoms of autism emerge
  in the latter part of the first or second years of life\, and therefore d
 iagnosis is not currently made until 2-4 years of age. Shen has demonstrat
 ed that enlargement of CSF volume emerged in the first six months of life 
 in infants who later developed autism\, allowing for the possibility of a 
 new\, earlier method of diagnosis. \n\nIn 2018\, Shen founded the clinical
  trials program within the Carolina Institute for Developmental Disabiliti
 es\, which tests novel genetic therapies in children with NDDs. The over-a
 rching goal of Shen’s research is to identify early biological markers a
 nd therapeutic targets for NDDs including autism\, fragile X syndrome\, Do
 wn syndrome\, and Angelman syndrome. His research is unique because it is 
 fully translational between preclinical models\, clinical research\, and c
 linical trials.
ATTACH;FMTTYPE=image/jpeg:https://researchweek.unc.edu/wp-content/uploads/
 2024/08/het-talks-photoswithlogo-scaled.jpg
CATEGORIES:Featured Event,In-person Event,Office of the Vice Chancellor
 for Research
LOCATION:Wilson Library\, Pleasants Family Assembly Room\, 201 South Road\,
  Chapel hill\, North Carolina\, 27515\, United States
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=201 South Road\, Chapel hil
 l\, North Carolina\, 27515\, United States;X-APPLE-RADIUS=100;X-TITLE=Wils
 on Library\, Pleasants Family Assembly Room:geo:0,0
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DTSTART:20240310T030000
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